Diabetes: Immune system can regulate insulin
Diabetes: Immune system can regulate insulin Inflammation processes are responsible for the failure of insulin production in diabetes patients. The patients' own immune systems can contribute to treatment of this disease: researchers at the University of Basel and University Hospital Basel have found a feedback mechanism that could help maintain insulin production in overweight sufferers, as they report in the journal Immunity. In their study, the Basel-based researchers focused specifically on recently discovered ILC2 immune cells in the pancreas, where, under diabetic conditions, the protein IL33 is activated, among others. This protein stimulates the ILC2 cells, which trigger the release of insulin in overweight individuals using retinoic acid and could therefore be used to inhibit the failure of insulin production. The research conducted by scientists at the Department of Endocrinology, Diabetes and Metabolism at University Hospital Basel and the University of Ba...